|Number of samples:||27|
|Release date:||Jun 12 2017|
|Last update date:||Nov 29 2018|
|Dataset link||Integrator complex subunit 12 is a key regulator of human protein synthesis pathways|
INTS12 depletion was induced in human bronchial epithelial cells from both donors. RNAseq gene expression profiling was performed 48h and 120h since the initiation of knockdown in the first and second donor respectively. Silencing was achieved with two independent D-siRNAs and experiments included scambled D-siRNA transfected and un-transfected cells. Experiments were performed in three biological replicates. Genome-wide INTS12 binding sites were inferred by INTS12 ChIPseq in two donor cells. ChIPseq experiment included input control pooled from both sequenced donors.
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