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Contains image and phenotype data for embryonic lethal knockout mice. DMDD is database allowing to search by gene, phenotype or tissue type. The data sheds new light on genes that are critical for embryo development and survival. High-resolution 3D image analysis and tissue histology are used to identify abnormalities in both embryos and placentas from embryonic lethal lines. It provides Full-resolution images, phenotypes annotated on the relevant images and Phenotype penetrance data for each line. The database also includes gene expression profiles for embryos from knockout lines.

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DMDD classification

  • Animals
    • Mus musculus

DMDD specifications

Unique identifier:
OMICS_11028
Restrictions to use:
None
Version:
2017.02
Maintained:
Yes
Name:
Deciphering the Mechanisms of Developmental Disorders
Data access:
Browse
Content license:
CC Attribution-NonCommercial-ShareAlike, Other

DMDD support

Maintainers

  • DMDD Team <>
  • Wolfgang Weninger <>

Credits

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Publications

Institution(s)

The Francis Crick Institute, London, UK

Funding source(s)

Supported by funding from the Wellcome Trust (WT100160), the Wellcome Trust (WT100160). It is also supported by the Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001157, FC001117), the UK Medical Research Council (FC001157, FC001117), the Wellcome Trust (FC001157, FC001117) and the Medical Research Council (U117562103).

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