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Allows detection of cell type-specific differential gene expression and molecular profile-based classification. deconf implements the deconfounding algorithm together with options for normalization, run-time options for the iteration process, and number of cell-type specific gene expression profiles to be estimated.

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deconf classification

deconf specifications

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deconf distribution


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deconf support


  • Dirk Repsilber <>


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Department of Genetics and Biometry, Research Institute for the Biology of Farm Animals, Dummerstorf, Germany; Bioinformatics Chair, Institute for Biochemistry and Biology at the University
of Potsdam, Potsdam-Golm, Germany; Molecular Biology and Human Genetics, University of Stellenbosch, Cape Town, South Africa; Department of Immunology, Max-Planck-Institute for Infection Biology, Berlin, Germany; Department of Immunology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany

Funding source(s)

Supported by the Grand Challenges in Global Health Project: Grant Number 37772.

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