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DeconRNASeq | A statistical framework for deconvolution of heterogeneous tissue samples based on mRNA-Seq data

A package for deconvolution of heterogeneous tissues based on mRNA-Seq data. DeconRNASeq adopts a globally optimized non-negative decomposition algorithm through quadratic programming for estimating the mixing proportions of distinctive tissue types in next-generation sequencing data. It encapsulates the method in a convenient-to-use format. The independent profile-generating module in DeconRNASeq grants freedom to users, who can combine with other R or Bioconductor packages to perform upstream and downstream analysis of NGS data.

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DeconRNASeq forum

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DeconRNASeq classification

DeconRNASeq specifications

Unique identifier:
OMICS_01230
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Maintained:
Yes

DeconRNASeq distribution

versioning

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DeconRNASeq support

Documentation

Credits

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Publications

Institution(s)

Biomarker Development, Translational Medicine, Novartis Institutes for BioMedical Research, Cambridge, MA, USA

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