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Deep mutational scanning data analysis bioinformatics software tools

Mutagenesis provides insight into proteins, but only recently have assays that couple genotype to phenotype been used to assess the activities of as many as 1 million mutant versions of a protein in a single experiment. This approach-'deep…
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dms_tools
Desktop

dms_tools

A software package to infer the impacts of mutations from deep mutational…

A software package to infer the impacts of mutations from deep mutational scanning data using a likelihood-based treatment of the mutation counts. Using dms_tools, one can infer the preference of…

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dms2dfe
Desktop

dms2dfe Deep Mutational Scanning data to Distribution of Fitness Effects

Provides utilities for downstream analysis such as identification of relative…

Provides utilities for downstream analysis such as identification of relative selection pressure, molecular constraints and visualizations of the data. dms2dfe is a tunable, open-source workflow that…

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Enrich
Desktop

Enrich

A tool for analyzing such deep mutational scanning data. Enrich identifies all…

A tool for analyzing such deep mutational scanning data. Enrich identifies all unique variants (mutants) of a protein in high-throughput sequencing datasets and can correct for sequencing errors…

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