bookmark Enrich Analyzes deep mutational scanning data. Enrich incorporates scoring methods applicable to deep mutational scans with any number of time points. It predicts variant scores and standard errors that mirror both sampling error and consistency between replicates. This software measures an enrichment ration to estimate fitness via the frequency of each variant before and after selection. It offers an alignment-free mode and an implementation of the Needleman-Wunsch global alignment algorithm to call insertion and deletion events.