DeepAlign specifications

Information


Unique identifier OMICS_03689
Name DeepAlign
Software type Application/Script
Interface Web user interface
Restrictions to use None
Input format PDB
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Sheng Wang <>

Information


Unique identifier OMICS_03689
Name DeepAlign
Restrictions to use None
Operating system Unix/Linux
Programming languages C, C++
Computer skills Advanced
Version 1.2
Stability Stable
Source code URL https://codeload.github.com/realbigws/DeepAlign/tar.gz/v1.135-2
Maintained Yes

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Maintainer


  • person_outline Sheng Wang <>

DeepAlign article

DeepAlign institution(s)
Provides automatic protein structure alignment. DeepAlign uses amino acid and local substructure substitution matrices, which are derived from evolutionarily-related protein pairs, and generate alignments highly consistent with manually-curated alignments. The interest of this method lies in its scoring function, which considering not only 3D geometric similarity, but also evolutionary information at the sequence and local substructure levels as well as hydrogen bonding similarity.
DeepAlign funding source(s)
Supported by the National Institutes of Health grant R01GM089753, the National Science Foundation grant DBI-0960390 and the National Science Foundation CAREER award CCF-1149811.

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