DEF specifications


Unique identifier OMICS_13368
Name DEF
Alternative name Dead-End Filler
Interface Web user interface
Restrictions to use None
Input data Model file, Metabolites dictionary, Reaction mapping, External reactions, Organism proteome sequence
Input format XML, TXT, FSA
Output data Metabolites flow into and out of the introduced compartment through exchange reactions, and reactions essential for maximum flux for the production/consumption of certain dead end metabolite.
Output format Reactants, Flux, Reaction, Products, Boolean_in_Draft
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Ming Chen <>

Publication for Dead-End Filler

DEF institution(s)
Department of Bioinformatics, College of Life Sciences, Zhejiang University, Hangzhou, China; Department of Bioinformatics, University of California, Los Angeles, Los Angeles, CA, USA
DEF funding source(s)
This work was supported in part by the National Natural Sciences Foundation of China (No. 31571366, 31371328), Science Technology Department of Zhejiang Province (No. 2015C32057), the Fundamental Research Funds for the Central Universities, Jiangsu Collaborative Innovation Center for Modern Crop Production and the Program for Innovative Research Team in Zhejiang University.

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