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Demultiplexing software tools | High-throughput sequencing data analysis

Demultiplexing software tools | High-throughput sequencing data analysis

Pooling multiple samples increases the efficiency and lowers the cost of DNA sequencing. One approach to multiplexing is to use short DNA indices to uniquely identify each sample. After sequencing, reads must be assigned in silico to the sample of origin, a process referred to as demultiplexing.

Source text:
(Renaudet al., 2015) deML: robust demultiplexing of Illumina sequences using a likelihood-based approach. Bioinformatics.

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