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DeNovoGear

A software tool for analyzing de novo mutations from familial and somatic tissue sequencing data. DeNovoGear uses likelihood-based error modeling to reduce the false positive rate of mutation discovery in exome analysis and fragment information to identify the parental origin of germ-line mutations.

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DeNovoGear forum

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DeNovoGear classification

DeNovoGear specifications

Software type:
Package/Module
Restrictions to use:
None
Programming languages:
C++
Computer skills:
Advanced
Stability:
Stable
Interface:
Command line interface
Operating system:
Unix/Linux
License:
GNU General Public License version 2.0
Version:
1.1.1
Maintained:
Yes

DeNovoGear distribution

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DeNovoGear support

Documentation

Credits

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Publications

Institution(s)

Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Center for Evolutionary Medicine and Informatics, The Biodesign Institute, Arizona State University, Tempe, AZ, USA; Genome Mutation and Genetic Disease Group, Wellcome Trust Sanger Institute, Cambridge, UK; School of Life Sciences, Arizona State University, Tempe, AZ, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA

Link to literature

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