Unlock your biological data
Protein dephosphorylation, which is an inverse process of phosphorylation, plays a crucial role in a myriad of cellular processes, including mitotic cycle, proliferation, differentiation, and cell growth. Compared with tyrosine kinase substrate and phosphorylation site prediction, there is a paucity of studies focusing on computational methods of predicting protein tyrosine phosphatase substrates and dephosphorylation sites.
(Wang et al., 2016) DephosSite: a machine learning approach for discovering phosphotase-specific dephosphorylation sites. Sci Rep.