Depmap specifications

Information


Unique identifier OMICS_28911
Name Depmap
Alternative name Cancer Dependency Map
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

Maintainers


  • person_outline William Hahn
  • person_outline Depmap Team

Publication for Cancer Dependency Map

Depmap citation

library_books

Functional genomics identifies specific vulnerabilities in PTEN deficient breast cancer

2018
PMCID: 5863852
PMID: 29566768
DOI: 10.1186/s13058-018-0949-3

[…] st cancer cell lines (step 3, Figs. and ). The studies we reanalyzed were (1) the Breast Functional Genomics study, comprising genome-scale shRNA screens of 77 breast cancer cell lines [, ]; (2) the Cancer Dependency Map study, comprising genome-scale shRNA screens of 501 cancer cell lines, including 34 from breast cancer [, , ]; and (3) the Kinase Dependency Profiles study, comprising kinome-sca […]

Depmap institution(s)
Broad Institute of Harvard and MIT, Cambridge, MA, USA; Dana-Farber Cancer Institute, Boston, MA, USA; Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA
Depmap funding source(s)
Supported by NIH U01 CA176058, NIH ICBP grant U54 CA112962, The Carlos Slim Foundation in Mexico through the Slim Initiative for Genomic Medicine, and commercial research grants from Novartis.

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