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Deregulated subnetwork detection software tools | Pathway analysis

The deregulation of cell signaling pathways plays an important role during tumor development. To identify such pathways a number of approaches have been developed during the past decade.Source text:(Stockel et al., 2013) NetworkTrail--a web service…
CPLEX
Desktop

CPLEX

Detectes deregulated subgraphs in biological networks based on expression…

Detectes deregulated subgraphs in biological networks based on expression differences of the involved genes or proteins. As input, CPLEX requires a biological network and a list of genes with scores…

NetworkTrail
Web

NetworkTrail

Enables the user to detect deregulated pathways and subgraphs in biological…

Enables the user to detect deregulated pathways and subgraphs in biological networks. NetworkTrail is a web service that allows non-experts to carry out network analyses without having to struggle…

OptDis
Desktop

OptDis Optimally Discriminative subnetwork markers

A network-based classification algorithm using color coding technique to…

A network-based classification algorithm using color coding technique to identify optimally discriminative subnetwork markers. Focusing on protein-protein interaction (PPI) networks, we apply our…

FiDePa
Desktop

FiDePa Finding Deregulated Paths

Aims at detecting the significantly deregulated signaling cascades in tumor…

Aims at detecting the significantly deregulated signaling cascades in tumor cells. The FiDePa algorithm interprets expression differences between tumor and normal tissue and relies on gene set…

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