DFprot statistics

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Citations per year

Number of citations per year for the bioinformatics software tool DFprot

Tool usage distribution map

This map represents all the scientific publications referring to DFprot per scientific context
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DFprot specifications


Unique identifier OMICS_26599
Name DFprot
Interface Web user interface
Restrictions to use None
Computer skills Basic
Source code URL http://chaconlab.org/multiscale-simulations/dfprot/df-down?task=callelement&format=raw&item_id=15&element=f85c494b-2b32-4109-b8c1-083cca2b7db6&method=download&args%5B0%5D=44802b9c8a6bc4e4c1322a4970fd5569
Maintained Yes


  • person_outline Pablo Chacon

Publication for DFprot

DFprot citations


Drug Like Protein–Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology

Mol Inform
PMCID: 4160817
PMID: 25254076
DOI: 10.1002/minf.201400040

[…] ucture-based in silico screening was performed by targeting the VEGF-binding zone of the extracellular domain D2 of VEGFR-1. As flexibility is known to be important at protein–protein interfaces, the DFprot server was used to investigate the possible plasticity of the D2 domain of VEGFR-1.[] Analysis of the X-ray structure (with the probe mapping algorithm ProtoMol implemented in the screening pac […]


Prediction of protein motions from amino acid sequence and its application to protein protein interaction

BMC Struct Biol
PMCID: 3245509
PMID: 20626880
DOI: 10.1186/1472-6807-10-20

[…] ormations of the same protein.Recently, web-based tools for predicting internal motion have been developed. For example, FlexOracle [] and HingeProt [] predict hinge regions in proteins. Furthermore, DFprot [] predicts main-chain deformability, which corresponds fundamentally to the internal motions described above.However, all these tools, along with NMA, offer only limited practical use because […]

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DFprot institution(s)
Centro de Investigaciones Biologicas, CSIC, Madrid, Spain; Department of Molecular Biology, The Scripps Research Institute La Jolla, CA, USA
DFprot funding source(s)
Supported by funds from BFU2004-01282 and Fundacion BBVA and NIH 1-R01-GM071872-01.

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