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OMIC
08479

DIANA-miRPath

A miRNA pathway analysis web-server, providing accurate statistics, while being able to accommodate advanced pipelines. mirPath can utilize predicted miRNA targets (in CDS or 3’-UTR regions) provided by the DIANA-microT-CDS algorithm or even experimentally validated miRNA interactions derived from DIANA-TarBase. These interactions (predicted and/or validated) can be subsequently combined with sophisticated merging and meta-analysis algorithms.

Specifications

Interface:
Web user interface
Restrictions to use:
None
Computer skills:
Basic
Version:
DIANA-miRPath version 3.0
Stability:
Stable
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Documentation & support

Maintainer

  • Artemis G. Hatzigeorgiou <arhatzig at uth.gr>

Credits

Institution(s)

DIANA-Lab, Department of Electrical & Computer Engineering, University of Thessaly, 382 21 Volos, Greece

Publications

  • (Vlachos et al., 2015) DIANA-miRPath v3.0: deciphering microRNA function with experimental support. Nucleic acids research.
    PMID: 25977294
  • (Vlachos et al., 2012) DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways. Nucleic acids research.
    PMID: 22649059
  • (Papadopoulos et al., 2009) DIANA-mirPath: Integrating human and mouse microRNAs in pathways. Bioinformatics.
    PMID: 19435746

Classification

  • Animals
    • Caenorhabditis elegans
    • Danio rerio
    • Drosophila melanogaster
    • Homo sapiens
    • Mus musculus
    • Rattus norvegicus

Literature

  • (Alexiou et al., 2009) Lost in translation: an assessment and perspective for computational microRNA target identification. Bioinformatics.
    PMID: 19789267
  • (Ding et al., 2012) Finding microRNA targets in plants: current status and perspectives. Genomics, proteomics & bioinformatics.
    PMID: 23200136
  • (Majoros et al., 2013) MicroRNA target site identification by integrating sequence and binding information. Nature methods.
    PMID: 23708386
  • (Mendes et al., 2009) Current tools for the identification of miRNA genes and their targets. Nucleic acids research.
    PMID: 19295136
  • (Akhtar et al., 2016) Bioinformatic tools for microRNA dissection. Nucleic acids research.
    PMID: 26578605

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