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DiANNA specifications


Unique identifier OMICS_04216
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for DiANNA

DiANNA citations


Cross talk of the biotrophic pathogen Claviceps purpurea and its host Secale cereale

PMCID: 5379732
PMID: 28372538
DOI: 10.1186/s12864-017-3619-4

[…] which did not match the “3 out of 4 programs predict a signal peptide” rule joined the final pool, if they contained at least 2 cysteines and at least one disulfide bond was predicted by either dianna 1.1 or disulfind 1.1 [–]. also proteins, which contained tms according to only one predicting program, were taken in the final pool, if they contained at least two cysteines and one predicted […]


Evidence for disulfide bonds in SR Protein Kinase 1 (SRPK1) that are required for activity and nuclear localization

PMCID: 5293202
PMID: 28166275
DOI: 10.1371/journal.pone.0171328

[…] be involved in disulfide bonding, with 414–427 being the most likely disulfide bond formed. however, the fact that cys414 is redundant for srpk1 activity invalidates this prediction. finally, the dianna 1.1 web server (http://clavius.bc.edu/~clotelab/dianna/) [] predicts the formation of multiple disulfide bonds, involving cys188, cys356, cys386, cys427 and cys455. interestingly, according […]


Truncated Variants of Gaussia Luciferase with Tyrosine Linker for Site Specific Bioconjugate Applications

PMCID: 4897649
PMID: 27271118
DOI: 10.1038/srep26814

[…] the locations of cystine disulfides in gluc were predicted using disulfind [http://disulfind.dsi.unifi.it/] (dipartimento di ingegneria dell’informazione, università di firenze, firenze, italy) and dianna 1.1 [http://clavius.bc.edu/clotelab/dianna/] (clote lab, boston college, chestnut hill, massachusetts)., hydrophobicity data for gluc was obtained from the protscale tool […]


Evolutionary Insights into IL17A in Lagomorphs

PMCID: 4692990
PMID: 26788019
DOI: 10.1155/2015/367670

[…] software and 1000 bootstrap replicates were used., the secondary structure of il17a was predicted using psipred (http://bioinf.cs.ucl.ac.uk/psipred/) [, ] and diaminoacid neural network application (dianna) (http://clavius.bc.edu/~clotelab/dianna/) []. both methods predict protein cysteines that create disulfide bonds, but while psipred uses position specific iterated-blast (psi-blast) to obtain […]


Genetic characterization of interleukins (IL 1α, IL 1β, IL 2, IL 4, IL 8, IL 10, IL 12A, IL 12B, IL 15 and IL 18) with relevant biological roles in lagomorphs

PMCID: 4609935
PMID: 26395994
DOI: 10.1177/1753425915606209

[…] only one sequence from each species was used., the secondary structure of each il was predicted using psipred (http://bioinf.cs.ucl.ac.uk/psipred/), and diaminoacid neural network application (dianna) (http://clavius.bc.edu/∼clotelab/dianna/). these methods predict protein cysteines that create permanent structural disulfide bonds. psipred uses position specific iterated–blast (psi-blast) […]


Comparative Analysis of Cystatin Superfamily in Platyhelminths

PMCID: 4390278
PMID: 25853513
DOI: 10.1371/journal.pone.0124683

[…] china). the specific primers are shown in ., signal peptides were predicted using signalp 4.0 (www.cbs.dtu.dk/services/signalp/) []. disulfide bonds and domain architecture were predicted using the dianna 1.1 web server [, ] and smart (http://smart.embl-heidelberg.de) [], respectively. the predicted 3d models of platyhelminth stefins and cystatins were constructed by the homology-modeling […]

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DiANNA institution(s)
Department of Biology, Boston College, Chestnut Hill, MA, USA

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