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DICHOT specifications


Unique identifier OMICS_06240
Restrictions to use None
Maintained No

Publication for DICHOT

DICHOT citations


Large scale aggregation analysis of eukaryotic proteins reveals an involvement of intrinsically disordered regions in protein folding

Sci Rep
PMCID: 5766493
PMID: 29330519
DOI: 10.1038/s41598-017-18977-5
call_split See protocol

[…] cted aggregation propensity was calculated by TANGO 2.3, whose binary program was obtained from the website (http://tango.crg.es/). The prediction of intrinsically disordered regions was performed by DICHOT algorithm,. Essentiality of each gene was obtained from the report by Giaever et al.. Protein abundance in the cell was obtained from the report by Huh et al.. The enrichment analysis based on […]


Amyotrophic Lateral Sclerosis Type 20 In Silico Analysis and Molecular Dynamics Simulation of hnRNPA1

PLoS One
PMCID: 4945010
PMID: 27414033
DOI: 10.1371/journal.pone.0158939

[…] eled structure, its secondary structure was predicted by PsiPred [], JuFo9D [] and Jpred [], and six disorder prediction algorithms were also consulted: FoldIndex [], Disopred [], ELM [], DisEMBL [], DICHOT [] and D2P2 []. […]


Multiple Localization and Hub Proteins

PLoS One
PMCID: 4902230
PMID: 27285823
DOI: 10.1371/journal.pone.0156455

[…] We analyzed the structures of NCP, CMP and NCMP, in terms of their intrinsic disorder and domain architectures. The results were compared with those from NP, CP and MP. The IDRs were predicted by DICHOT []. The P-fam domains [] were assigned by HMMER []. The distributions of the protein length, the percentage of IDR, and the longest IDR length are shown in , along with the average percentage o […]


A Method for Systematic Assessment of Intrinsically Disordered Protein Regions by NMR

Int J Mol Sci
PMCID: 4519922
PMID: 26184172
DOI: 10.3390/ijms160715743

[…] ion methods based on amino acid sequence analysis have succeeded [,,,]. Examples of the prediction tools in this category include DisEMBLE [], GlobProt [], PONDR, DISOPRED [], DISpro [], VSL2 [], and DICHOT []. We have also developed a series of web applications named POODLE [,,]. In designing the POODLE suite, we implemented three different programs (POODLE-S, POODLE-L, and POODLE-W) according to […]


Development of an accurate classification system of proteins into structured and unstructured regions that uncovers novel structural domains: its application to human transcription factors

BMC Struct Biol
PMCID: 2687452
PMID: 19402914
DOI: 10.1186/1472-6807-9-26

[…] The DICHOT system was constructed by combining three methods of structural domain identification, disorder prediction by DISOPRED2, and classification by the CLADIST program. Figure shows a flow chart of […]

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DICHOT institution(s)
Center for Information Biology and DNA Data Bank of Japan; National Institute of Genetics, Yata, Mishima, Shizuoka, Japan

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