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Differential translation identification software tools | Ribosome profiling data analysis

Global analysis of translation regulation has recently been enabled by the development of Ribosome Profiling, or Ribo-seq, technology. This approach provides maps of ribosome activity for each expressed gene in a given biological sample.…
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diricore
Desktop

diricore DIfferential-RIbosome-measurements-of-Codon-REading

Allows uncovering of amino acid limitations. diricore is an approach that was…

Allows uncovering of amino acid limitations. diricore is an approach that was applied to a cellular model in which epithelial cells respond rapidly to TGFb1 and was used to study TGFb1-induced…

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Xtail
Desktop

Xtail

Allows users to quantify the magnitudes and statistical significances of…

Allows users to quantify the magnitudes and statistical significances of differential translations at the genome-wide scale with ribosome profiling data. Xtail is able to identify the significant…

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Babel
Desktop

Babel

An analytical methodology for assessing the significance of changes in…

An analytical methodology for assessing the significance of changes in translational regulation within cells and between conditions. This approach facilitates the analysis of translation genome-wide…

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RiboDiff
Desktop

RiboDiff

Detects the protein translational efficiency change from Ribo-Seq (ribosome…

Detects the protein translational efficiency change from Ribo-Seq (ribosome footprinting) and RNA-Seq data. RiboDiff uses a generalized linear model to detect genes showing difference in…

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tRanslatome
Desktop

tRanslatome

Provides a complete platform for the simultaneous pairwise analysis of…

Provides a complete platform for the simultaneous pairwise analysis of transcriptome, translatome and proteome data. tRanslatome includes most of the available statistical methods developed for the…

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TranslatomeDB
Dataset

TranslatomeDB

Collects the RNC-seq, Ribo-seq and the corresponding mRNA-seq data from Gene…

Collects the RNC-seq, Ribo-seq and the corresponding mRNA-seq data from Gene Expression Omnibus (GEO) and Short Read Archive (SRA) databases. TranslatomeDB is an online resource that offers…

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anota2seq
Desktop

anota2seq

Allows users to analyze translatomes. anota2seq analyzes both differential…

Allows users to analyze translatomes. anota2seq analyzes both differential translation and differential translational buffering using data on a continuous scale or count data. The software has…

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Riborex
Desktop

Riborex

Maps genome-wide differences in translation efficiency. Riborex directly…

Maps genome-wide differences in translation efficiency. Riborex directly leverages established RNA-seq analysis frameworks for all parameter estimation, providing users with a choice among robust…

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ANOTA
Desktop

ANOTA ANalysis Of Translational Activity

Implements analysis of partial variance and allows scrutiny of associated…

Implements analysis of partial variance and allows scrutiny of associated statistical assumptions. ANOTA also provides biologically motivated filters for analysis of genome wide datasets. It was…

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