DiffSplice specifications

Information


Unique identifier OMICS_01330
Name DiffSplice
Software type Application/Script, Package/Module
Interface Command line interface
Restrictions to use None
Input data RNA-seq alignment files.
Input format SAM
Output data Alternative splicing modules (ASMs).
Output format GTF + TXT
Operating system Unix/Linux, Mac OS
Computer skills Advanced
Version 0.1.2
Stability Beta
Requirements g++
Maintained Yes

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Maintainer


  • person_outline Jinze Liu <>

DiffSplice article

DiffSplice citation

2013
PMCID: 3691247

[…] to identify alternative splicing (as) events, we used mats [20], a computational tool that detects differential as events from rna-seq data. we favored mats over other tools (e.g., miso [21] and diffsplice [22]) because of our experimental design and the ease of use and robustness of the program. mats tests that the difference in the exon or intron inclusion level of a gene (defined […]

DiffSplice institution(s)
Department of Computer Science, University of Kentucky, Lexington, KY, USA; UNC Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA ; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA ; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA ; Department of Statistics and Operations Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
DiffSplice funding source(s)
Supported by US National Institutes of Health [R01-HG006272]; US National Science Foundation [EF-0850237], NSF Career award [IIS-1054631], National Institutes of Health grants [RC1-HL100108, AA017376, U24-CA143848 and 3U24-CA143848-02S1, R01-CA149569-03] and UNC University Cancer Research Fund.

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