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Diplotyper

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Combines an algorithm designed to cluster haplotypes of interest from a given set of haplotypes with two existing tools: Haploview, for analyses of linkage disequilibrium blocks and haplotypes, and PLINK, to generate all possible diplotypes from given genotypes of samples and calculate linear or logistic regression. In addition, procedures for generating all possible diplotypes from the haplotype clusters and transforming these diplotypes into PLINK formats were implemented. Diplotyper is a fully automated tool for performing association analysis based on diplotypes in a population. Diplotyper is useful for identifying more precise and distinct signals over single-locus tests.

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Diplotyper classification

Diplotyper specifications

Software type:
Package/Module
Restrictions to use:
None
License:
GNU General Public License version 3.0
Stability:
Stable
Interface:
Command line interface
Operating system:
Unix/Linux, Windows
Computer skills:
Advanced
Maintained:
Yes

Diplotyper distribution

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Credits

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Publications

Institution(s)

Department of Biomedical Science, College of Life Science, CHA University, Seongnam, Korea; Department of Family Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea; Department of Preventive Medicine, Ajou University School of Medicine, Suwon, Korea; Department of Physiology, College of Medicine, Hanyang University, Seoul, Korea

Funding source(s)

This study was supported by a grant from the Korea Health technology R&D Project, Ministry of Health & Welfare, Republic of Korea (A110749), grants from Korea Centers for Disease Control and Prevention (4845-301, 4851-302, 4851-307), and the Priority Centers Program of the National Research Foundation of Korea (NRF), which is funded by the Ministry of Education, Science, and Technology (No. 2009-0093821).

Link to literature

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