DISCO specifications


Unique identifier OMICS_23355
Alternative name DIstance and Spectrum Correlation Optimization
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data Some outputs of the instrument control software ChromaTOF
Operating system Unix/Linux
Programming languages MATLAB
Computer skills Advanced
Stability Alpha
Maintained Yes




No version available


  • person_outline Xiang Zhang

Publication for DIstance and Spectrum Correlation Optimization

DISCO citation


Comparative Analysis of Mass Spectral Similarity Measures on Peak Alignment for Comprehensive Two Dimensional Gas Chromatography Mass Spectrometry

PMCID: 3787630
PMID: 24151524
DOI: 10.1155/2013/509761

[…] ignment using Smith-Waterman local alignment algorithm. Of these methods, MbPA is the only model-based approach, which uses an empirical Bayes model and the posterior distribution for peak alignment. DISCO, SWPA, and MbPA can be applied to both homogeneous and heterogeneous data, while MSort and mSPA are able to align only for homogeneous data. The homogeneous data mean that all samples were analy […]

DISCO institution(s)
Department of Chemistry, University of Louisville, Louisville, KY, USA; LECO Corporation, St. Joseph, MI, USA
DISCO funding source(s)
Supported by NIH Grant 1RO1GM087735-01.

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