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Disease similarity identification software tools | Health sciences

Elucidation of human disease similarities has provided new insights into etiology, disease classification and drug repositioning.Source text:(Yang et al., 2015) DSviaDRM: an R package for estimating disease similarity via dysfunctional regulation…
CTD
Dataset

CTD Comparative Toxicogenomics Database

Provides information about interactions between environmental chemicals and…

Provides information about interactions between environmental chemicals and gene products and their relationships to diseases. Chemical-gene, chemical-disease and gene-disease interactions manually…

DTMiner
Web

DTMiner

A framework for the automatic extraction of gene-disease relation from…

A framework for the automatic extraction of gene-disease relation from biomedical literature. DTMiner takes large biomedical literature repositories as inputs, identifies credible relationships…

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MORPHIN
Web

MORPHIN Model Organisms Projected on a Human Integrated Gene Network

A web-based discovery tool for human disease studies. MORPHIN investigates…

A web-based discovery tool for human disease studies. MORPHIN investigates human diseases by an orthology-based projection of a set of model organism genes onto a genome-scale human gene network.…

DSviaDRM
Desktop

DSviaDRM

An R package to identify significant disease similarity (DS) via dysfunctional…

An R package to identify significant disease similarity (DS) via dysfunctional regulation mechanism (DRM) based on transcriptomic data. DSviaDRM contains five easy-to-use functions, DCEA, DCpathway,…

DisGeNET
Web

DisGeNET

A comprehensive discovery platform designed to address a variety of questions…

A comprehensive discovery platform designed to address a variety of questions concerning the genetic underpinning of human diseases. DisGeNET contains over 380,000 associations between >16,000…

DiseaseConnect
Web

DiseaseConnect

A web server for analysis and visualization of a comprehensive knowledge on…

A web server for analysis and visualization of a comprehensive knowledge on mechanism-based disease connectivity. DiseaseConnect integrates comprehensive omics and literature data, including a large…

MedNetSim
Web

MedNetSim

A method for computing disease similarity by integrating medical literature and…

A method for computing disease similarity by integrating medical literature and protein interaction network. MedNetSim consists of a network-based method (NetSim), which employs the entire protein…

SemFunSim
Algorithm

SemFunSim Semantic Functional Similarity

Measures disease similarity by integrating FunSim and SemSim effectively.…

Measures disease similarity by integrating FunSim and SemSim effectively. FunSim is proposed to calculate disease similarity using disease-related gene sets in a weighted network of human gene…

PHENOstruct
Desktop

PHENOstruct

Predicts a set of hierarchically consistent human phenotype ontology (HPO)…

Predicts a set of hierarchically consistent human phenotype ontology (HPO) terms for a given gene. PHENOstruct learns a compatibility function that models the association between a given input and a…

DOSim
Desktop

DOSim

An R-based software package to compute the similarity between diseases and to…

An R-based software package to compute the similarity between diseases and to measure the similarity between human genes in terms of diseases. DOSim incorporates a DO-based enrichment analysis…

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