DiseaseConnect

[…] pid, of which 223 pathways were selected from the nci-nature curated database, 254 pathways were collected from the biocarta database, and 838 pathways were obtained from the reactome database., diseaseconnect (http://disease-connect.org/) is a public web-server for the analysis and visualization of comprehensive knowledge regarding common molecular mechanism-based disease-disease […]

[…] organized in a hierarchical tree[,]. based on the 23 mesh headings, which were extrapolated manually by trained experts, we searched the coremine pubmed search engine system[], the omim[], and the diseaseconnect[] databases to extract disease-gene relationships. moreover, we manually examined and verified disease-gene co-occurrence in the literature contained in the pubmed database, in order […]

[…] between the modules and curated ais-related genes. the curated ais-related genes were extracted from three phenotype-genotype associations, including the coremine literature database, omim and diseaseconnect. the human interactome data were filtered from the string 9.1 ppi database. we used a widely used community detection method (i.e., bgll) to identify topological modules […]

[…] proteins (genes) found for each hpa categories. we then compared the number of publications between categories to evaluate the possibility of publication bias (student t-test)., the diseaseconnect database, which associates genes with diseases, was used to link cofactor-interacting proteins to diseases. for the present analysis, data from omim (which included 3,644 genes […]

[…] of differential expression values of protein interaction modules between different diseases as the disease similarity measure, and found out 138 significant similarities between diseases []. diseaseconnect, a web server, also utilized differentially expressed genes to explore disease relationships []. these studies adopted a common understanding that diseases are highly correlated […]