DiseaseConnect statistics
DiseaseConnect specifications
Information
Unique identifier | OMICS_04646 |
---|---|
Name | DiseaseConnect |
Interface | Web user interface |
Restrictions to use | None |
Computer skills | Basic |
Stability | Stable |
Maintained | Yes |
Taxon
-
Primates
- Homo sapiens
Maintainer
- person_outline Chun-Chi Liu <>
Publication for DiseaseConnect
DiseaseConnect: a comprehensive web server for mechanism-based disease-disease connections.
DiseaseConnect in publications
(6)Functional diversity of topological modules in human protein protein interaction networks
[…] pid, of which 223 pathways were selected from the nci-nature curated database, 254 pathways were collected from the biocarta database, and 838 pathways were obtained from the reactome database., diseaseconnect (http://disease-connect.org/) is a public web-server for the analysis and visualization of comprehensive knowledge regarding common molecular mechanism-based disease-disease […]
Integrated network analysis reveals potentially novel molecular mechanisms and therapeutic targets of refractory epilepsies
[…] organized in a hierarchical tree[,]. based on the 23 mesh headings, which were extrapolated manually by trained experts, we searched the coremine pubmed search engine system[], the omim[], and the diseaseconnect[] databases to extract disease-gene relationships. moreover, we manually examined and verified disease-gene co-occurrence in the literature contained in the pubmed database, in order […]
[…] between the modules and curated ais-related genes. the curated ais-related genes were extracted from three phenotype-genotype associations, including the coremine literature database, omim and diseaseconnect. the human interactome data were filtered from the string 9.1 ppi database. we used a widely used community detection method (i.e., bgll) to identify topological modules […]
A network analysis of cofactor protein interactions for analyzing associations between human nutrition and diseases
[…] proteins (genes) found for each hpa categories. we then compared the number of publications between categories to evaluate the possibility of publication bias (student t-test)., the diseaseconnect database, which associates genes with diseases, was used to link cofactor-interacting proteins to diseases. for the present analysis, data from omim (which included 3,644 genes […]
[…] of differential expression values of protein interaction modules between different diseases as the disease similarity measure, and found out 138 significant similarities between diseases []. diseaseconnect, a web server, also utilized differentially expressed genes to explore disease relationships []. these studies adopted a common understanding that diseases are highly correlated […]
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