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DISIS specifications


Unique identifier OMICS_08392
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability No
Maintained No


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DISIS citations


Optimizing recovery of frozen human peripheral blood mononuclear cells for flow cytometry

PLoS One
PMCID: 5665600
PMID: 29091947
DOI: 10.1371/journal.pone.0187440

[…] cell viability when using pre-heated (37°c) washing medium, but when the wash medium was cooled, and mixed rapidly with pbmcs, the viability was lower. a lower cell viability was also described by disis et al. [] when using washing medium at 4°c. thus, previous reports suggest the use of pre-heated, 37°c medium. furthermore, we found that thawing pbmcs until only a small amount of ice remains […]


Estimating seroprevalence of herpes simplex virus type 1 among different Middle East and North African male populations residing in Qatar

PMCID: 5724503
PMID: 28817197
DOI: 10.1002/jmv.24916

[…] work and administrative support of ms enas alabsi and ms adona canlas, and the following students for their assistance in performing the anti‐hsv‐1 elisa assay testing: mariam nofal, rana al‐disis, malaz comi, afifah sahara, and sana khan. we are also grateful to dr asmaa al‐marwani, ms maria samatti, and ms sana abohasera for their work on blood specimen collection. the authors […]


Scholarly productivity and professional advancement of junior researchers receiving KL2, K23, or K08 awards at a large public research institution

PMCID: 5471825
PMID: 28649457
DOI: 10.1017/cts.2016.22

[…] nih funding and progress to the rank of associate professor, and a large majority continues in research in academic settings., this work was funded, in part, by grants ul1tr000423 and kl2tr000421 (disis) and k24 k24hd082231 (amory)., author contributions , j.k.a. wrote the manuscript, designed the study, analyzed data; d.k.n.l. designed the study, performed data collection; c.m. wrote […]


Dose Titration Algorithm Tuning (DTAT) should supersede ‘the’ Maximum Tolerated Dose (MTD) in oncology dose finding trials

PMCID: 5473410
PMID: 28663782
DOI: 10.5256/f1000research.11448.r20080

[…] important role that fail-safe upper bounds on both absolute dose and dose multipliers will play in reducing the risk of overshooting in a practical trial., references weber js, yang jc, atkins mb, disis ml. toxicities of immunotherapy for the practitioner. jco. 2015;33(18):2092-2099. doi:10.1200/jco.2014.60.0379.postel-vinay s, gomez-roca c, molife lr, et al. phase i trials of molecularly […]


The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy

Endocr Relat Cancer
PMCID: 5425956
PMID: 28193698
DOI: 10.1530/ERC-16-0404

[…] are not highly common in breast cancer, the literature provides clear examples of neoantigen recognition and the generation of an immune response. in a small patient cohort with her2+ breast cancer, disis and coworkers demonstrated cd4+ helper/inducer t-cell immunity and antibody-mediated immunity to her-2/neu protein (). a lower level of her2 t-cell immunity has been proposed as a prognostic […]


Incorporation of GM CSF or CD40L Enhances the Immunogenicity of Hantaan Virus Like Particles

PMCID: 5167722
PMID: 28066721
DOI: 10.3389/fcimb.2016.00185

[…] immune responses and affect th1/th2 cytokine balance. gm-csf has been extensively used as an effective genetic and protein adjuvant to enhance the immunogenicity of tumor and vaccine antigens (disis et al., ; kass et al., ; poloso et al., ; skountzou et al., ; chou et al., )., another immunostimulatory molecule is the cd40 ligand (cd40l), which is a surface molecule […]

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DISIS institution(s)
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA

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