Reproduces HMMER2/3 scores with sufficient accuracy and that it is useful in automated decisions about homology for instructive sequence examples. DissectHMMER is a software program for dissecting HMMER2/3 scores into segment-specific contributions. It was written to compute the reconstructed score relative to predefined alignment segments using the alignment (the HMM output) and the HMM model file as inputs independent on the HMMER suite version used
Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Matrix, Singapore, Singapore; School of Biological Sciences (SBS), Nanyang Technological University (NTU), Singapore, Singapore; Department of Biological Sciences (DBS), National University of Singapore (NUS), Singapore, Singapore; School of Computer Engineering (SCE), Nanyang Technological University (NTU), Singapore, Singapore
dissectHMMER funding source(s)
This work was supported by A*STAR Singapore, the grants “A*STAR-NKTH JGC 007”, “SERC IMaGIN”, and “IAF CAT3 Integrated Genomics Platform”.