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Protocols

diXa specifications

Information


Unique identifier OMICS_06808
Name diXa
Alternative name Data Infrastructure for Chemical Safety Assessment
Restrictions to use None
Maintained Yes

Publication for Data Infrastructure for Chemical Safety Assessment

diXa citations

 (3)
call_split

Ab initio chemical safety assessment: A workflow based on exposure considerations and non animal methods

2017
PMCID: 5695905
PMID: 29214231
DOI: 10.1016/j.comtox.2017.10.001
call_split See protocol

[…] and finally to possible adverse outcomes .‘Omics data for chemical x were generated within the FP6-carcinoGENOMICS project and are available in the Data Infrastructure for Chemical Safety warehouse (diXa). The data represent three in vitro human hepatocytes models: HepaRG (human hepatoma-derived cells), HepG2 (hepatocellular carcinoma-derived cell line) and hES-DE-Hep (hepatocyte-like cells deriv […]

library_books

A transcriptomics data driven gene space accurately predicts liver cytopathology and drug induced liver injury

2017
Nat Commun
PMCID: 5500850
PMID: 28671182
DOI: 10.1038/ncomms15932

[…] dbc.jp/en/open-tggates/download.html) and custom processed, unless otherwise stated. Raw data is also available at ArrayExpress (E-MTAB-800, E-MTAB-799, E-MTAB-798 and E-MTAB-797) and through the EBI Dixa data warehouse (http://wwwdev.ebi.ac.uk/fg/dixa/index.html): diXa-005, DIXA-006 and DIXA-008. As detailed by the creators, the data assayed 143 compounds on 6765 genome-wide microarrays and 1689 […]

library_books

Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26–27 June 2013, Research Triangle Park, NC, USA

2014
PMCID: 4247478
PMID: 25326818
DOI: 10.1007/s00204-014-1387-3

[…] The diXa infrastructure (http://www.dixa-fp7.eu/) consists of a central data warehouse containing data from toxicogenomics project repositories and public databases. Apart from data from European projects […]

Citations

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diXa institution(s)
Department of Toxicogenomics, School of Oncology and Developmental Biology (GROW), Maastricht University, Netherlands; Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambs, UK; Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, South Kensington, London, UK; Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, Netherlands; Genedata AG, Basel, Switzerland; Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany; Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, Cologne, Germany; European Commission, Joint Research Centre, Ispra VA, Italy

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