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diXa specifications


Unique identifier OMICS_06808
Name diXa
Alternative name Data Infrastructure for Chemical Safety Assessment
Restrictions to use None
Maintained Yes

Publication for Data Infrastructure for Chemical Safety Assessment

diXa citations


Ab initio chemical safety assessment: A workflow based on exposure considerations and non animal methods

PMCID: 5695905
PMID: 29214231
DOI: 10.1016/j.comtox.2017.10.001
call_split See protocol

[…] and finally to possible adverse outcomes .‘Omics data for chemical x were generated within the FP6-carcinoGENOMICS project and are available in the Data Infrastructure for Chemical Safety warehouse (diXa). The data represent three in vitro human hepatocytes models: HepaRG (human hepatoma-derived cells), HepG2 (hepatocellular carcinoma-derived cell line) and hES-DE-Hep (hepatocyte-like cells deriv […]


A transcriptomics data driven gene space accurately predicts liver cytopathology and drug induced liver injury

Nat Commun
PMCID: 5500850
PMID: 28671182
DOI: 10.1038/ncomms15932

[…] dbc.jp/en/open-tggates/download.html) and custom processed, unless otherwise stated. Raw data is also available at ArrayExpress (E-MTAB-800, E-MTAB-799, E-MTAB-798 and E-MTAB-797) and through the EBI Dixa data warehouse (http://wwwdev.ebi.ac.uk/fg/dixa/index.html): diXa-005, DIXA-006 and DIXA-008. As detailed by the creators, the data assayed 143 compounds on 6765 genome-wide microarrays and 1689 […]


Workshop report: Identifying opportunities for global integration of toxicogenomics databases, 26–27 June 2013, Research Triangle Park, NC, USA

PMCID: 4247478
PMID: 25326818
DOI: 10.1007/s00204-014-1387-3

[…] The diXa infrastructure (http://www.dixa-fp7.eu/) consists of a central data warehouse containing data from toxicogenomics project repositories and public databases. Apart from data from European projects […]


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diXa institution(s)
Department of Toxicogenomics, School of Oncology and Developmental Biology (GROW), Maastricht University, Netherlands; Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambs, UK; Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, South Kensington, London, UK; Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, Netherlands; Genedata AG, Basel, Switzerland; Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany; Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, Cologne, Germany; European Commission, Joint Research Centre, Ispra VA, Italy

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