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DMDD specifications

Information


Unique identifier OMICS_11028
Name DMDD
Alternative name Deciphering the Mechanisms of Developmental Disorders
Restrictions to use None
Data access Browse
Version 2017.02
Content license CC Attribution-NonCommercial-ShareAlike, Other
Maintained Yes

Taxon


  • Rodents
    • Mus musculus

Maintainers


  • person_outline DMDD Team
  • person_outline Wolfgang Weninger

Publications for Deciphering the Mechanisms of Developmental Disorders

DMDD citations

 (7)
library_books

Designing image segmentation studies: Statistical power, sample size and reference standard quality

2017
Med Image Anal
PMCID: 5666910
PMID: 28772163
DOI: 10.1016/j.media.2017.07.004

[…] underestimated the simulated power which could lead to inefficient resource usage, but would not lead to failed studies caused by insufficient power. When using a low-quality reference standard with δMDD defined with respect to a high-quality reference standard, the error was also correlated with skew. However, in this context, another source of error must be considered: error in the estimation o […]

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Morphology, topology and dimensions of the heart and arteries of genetically normal and mutant mouse embryos at stages S21–S23

2017
J Anat
PMCID: 5603791
PMID: 28776665
DOI: 10.1111/joa.12663
call_split See protocol

[…] lysed the phenotype of a total of 474 E14.5 mouse embryos (298 mutants and 176 controls) bred from the C57BL/6N strain at the Wellcome Trust Sanger Institute (http://www.sanger.ac.uk/) as part of the DMDD project (https://dmdd.org.uk/) and its pilot (Mohun et al. ; Weninger et al. ). All embryos were carefully staged using forelimb maturation (Geyer et al. ). As the number of controls of S21 and S […]

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The microprotein Minion controls cell fusion and muscle formation

2017
Nat Commun
PMCID: 5461507
PMID: 28569745
DOI: 10.1038/ncomms15664
call_split See protocol

[…] RNAseq analysis of early embryonic development was from the Deciphering the Mechanisms of Developmental Disorders progam via EMBL-EBI Expression Atlas (https://www.ebi.ac.uk/gxa). The data set was interrogated using the following Ensembl IDs: mouse Minion/gm73 […]

library_books

The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection

2015
Nucleic Acids Res
PMCID: 4702933
PMID: 26740669
DOI: 10.1093/nar/gkv1356

[…] s, bees and wasps (Hymenoptera Genome Database), cow and mouse. The new arrivals include a collection of insect genome resources and genome databases of planaria and ascidians (–). A very interesting Deciphering the Mechanisms of Developmental Disorders (DMDD) database collects phenotypic data of mouse mutant embryos (). This section also includes the database of autosomal monoallelic gene express […]

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Tuber shape and eye depth variation in a diploid family of Andean potatoes

2015
BMC Genet
PMCID: 4448561
PMID: 26024857
DOI: 10.1186/s12863-015-0213-0
call_split See protocol

[…] Separate parental maps of ‘DMDD’ population were constructed using marker data previously developed by the Potato Genome Sequencing Consortium (PGSC) to construct genetic and physical maps for ‘DMDD’ []. Genetic maps were estab […]

library_books

Construction of Reference Chromosome Scale Pseudomolecules for Potato: Integrating the Potato Genome with Genetic and Physical Maps

2013
PMCID: 3815063
PMID: 24062527
DOI: 10.1534/g3.113.007153

[…] s. This issue was resolved by using additional resources that we refer to as the in silico anchoring approach. For example, the large block of “orphaned” superscaffolds, not directly connected to the DMDD map, stretching from DMB 394 to DMB 705 (with the exception of DMBs 193, 15, 59, 100, and 200) on chromosome 1 (see ) was anchored by the evidence derived from the WGP/AFLP-based RH map and the t […]

Citations

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DMDD institution(s)
The Francis Crick Institute, London, UK
DMDD funding source(s)
Supported by funding from the Wellcome Trust (WT100160), the Wellcome Trust (WT100160). It is also supported by the Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001157, FC001117), the UK Medical Research Council (FC001157, FC001117), the Wellcome Trust (FC001157, FC001117) and the Medical Research Council (U117562103).

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