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DN-Fold specifications


Unique identifier OMICS_10826
Name DN-Fold
Interface Web user interface
Restrictions to use None
Input data Plain protein sequence
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Jianlin Cheng

Publication for DN-Fold

DN-Fold citations


miR 217 Is a Useful Diagnostic Biomarker and Regulates Human Podocyte Cells Apoptosis via Targeting TNFSF11 in Membranous Nephropathy

Biomed Res Int
PMCID: 5682891
PMID: 29214160
DOI: 10.1155/2017/2168767

[…] he results showed that, compared with control patients, the expression of miR-217 was not statistically different in renal tissue and plasma from FSGS, was significantly upregulated in those from the DN (fold change = 4.27 in renal tissue, fold change = 3.25 in plasma), and was significantly downregulated in those from MN (fold change = −6.95 in renal tissue, fold change = −4.12 in plasma) (Figure […]


Adaptive local learning in sampling based motion planning for protein folding

BMC Syst Biol
PMCID: 4977477
PMID: 27490494
DOI: 10.1186/s12918-016-0297-9

[…] rees that are each trained on datasets of target-template protein pairs. RF-Fold recognition rate is comparable to the best performance in fold recognition at the family, superfamily, and fold levels.DN-Fold is another fold recognition technique, but it uses a deep learning neural network as a basis for learning []. A deep learning network has many more layers than a typical neural network. In add […]


Dynamic recruitment of Ets1 to both nucleosome occupied and depleted enhancer regions mediates a transcriptional program switch during early T cell differentiation

Nucleic Acids Res
PMCID: 4856961
PMID: 26673693
DOI: 10.1093/nar/gkv1475

[…] s also in light of previous reports having linked in vivo T-cell differentiation with distal rather than proximal regulation (). We computed and sorted the union of distal peaks by increasing Ets1 DP/DN fold change (DN + DP peaks, 3900 sites, see Supplementary Table S4 for a complete list) and subdivided them into five distinct classes (also corresponding to unique densities of Ets1 DN or DP signa […]


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DN-Fold institution(s)
Department of Computer Science, University of Missouri, Columbia, MO, USA; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, USA; Department of Computer Science, Central Michigan University, Mount Pleasant, MI, USA

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