Integrates manually curated information on the human DNA damage response network and its sub-pathways. DDRprot is presented within an evolutionary framework that allows many features to be explored and as such, we believe it will be very useful to researchers in the field. DDRprot database can be queried by different criteria: pathways, species, evolutionary age or post-translational modifications. Sequence searches using hidden Markov models can be also used.
Computational Biology and Bioinformatics Group, Institute of Biomedicine of Seville, Sevilla, Spain; Cell Movements in Development and Disease Lab, Instituto de Neurociencias (CSIC-UMH), Alicante, Spain
DDRprot funding source(s)
Supported by the European Commission grant [FP7-REGPOT-2012-2013-1; the Spanish Ministry of Science and Innovation grant [PS09/02111].