DNA Methylation Age Calculator statistics

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DNA Methylation Age Calculator specifications

Information


Unique identifier OMICS_27101
Name DNA Methylation Age Calculator
Interface Web user interface
Restrictions to use None
Biological technology Illumina
Computer skills Basic
Stability Stable
Registration required Yes
Maintained Yes

Documentation


Maintainer


  • person_outline Steve Horvath <>

DNA Methylation Age Calculator in publications

 (5)
PMCID: 5907301
PMID: 29713391
DOI: 10.1186/s13148-018-0481-4

[…] cells in a sample. after previously reported qc, methylation data were available for 461,281 5′-cytosine-phosphate-guanine-3′ genomic site (cpgs) []. the non-normalized data were uploaded into the dna methylation age calculator [] using the advanced analysis in blood option. we removed 140 samples for which the predicted tissue was not blood. to err on the side of caution, we removed 23 […]

PMCID: 5636670
PMID: 28930701
DOI: 10.18632/aging.101293

[…] that to gain further mechanistic insight, the focus of studying both ltl and epigenetic age should be shifted from adults to children., finally, our findings are based on imputation using the dna methylation age calculator (materials and methods) rather than direct measurements of the numbers of t cells. there is no reason to believe that direct measurements of t cells would […]

PMCID: 5119954
PMID: 27863251
DOI: 10.1016/j.cell.2016.10.026

[…] if the concordance rate was greater than 90%., for dna methylation, first we estimated sex and age of all samples based on raw dna methylation values using the getsex function in minfi () and the dna methylation age calculator as described by horvath (), respectively. we then correlated the estimated information from the experimental data to the information collected from each donor, […]

PMCID: 4990229
PMID: 27245352
DOI: 10.1080/15592294.2016.1192736

[…] control) and gestational age in the regression model, only 83 sites were differentially (42 hyper- and 41 hypo-) methylated during development between ds and control brains. when we applied the dna methylation age calculator, which relies on only 353 cpg sites, to our fetal brain samples, it correctly predicted prenatal (negative) age. the gestational age was positively correlated with dna […]

PMCID: 4838528
PMID: 27103889
DOI: 10.5808/GI.2016.14.1.34

[…] age information, as well, we tested whether the given age information deviated much from the estimated age from age-specific dna methylation markers. the age prediction was performed by using the dna methylation age calculator, a web-based tool that provides a predicted age based on the methylation values of dna methylation markers of illumina's infinium platform []. when we compared […]


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DNA Methylation Age Calculator funding source(s)
Supported by NIH 5R01AG042511-02.

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