DNA modifications analysis software tools | Epigenomics
Whole genome DNA methylation detection is one of the most important part of epigenetics research. It is supposed to have a great effect on cancers and tumors, and even be involved in the senility of human. In addition, it is believed that in medical aspects, DNA methylation may have a strong relationship with diabetes and immunological diseases (Jeong et al., 2014; Hackett et al., 2013; Duthie, 2011).
(Jeong et al., 2014) Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet.
(Hackett et al., 2013) DNA methylation dynamics during the mammalian life cycle. Philos Trans R Soc Lond.
( Duthie, 2011) Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis. J Inherit Metab Dis.
(Peng et al., 2017) P-Hint-Hunt: a deep parallelized whole genome DNA methylation detection tool. BMC Genomics.