DNA-Protein interactions databases

Chromatin is a genome-organizing platform, regulating gene expression, cell division and differentiation, etc. Epigenetic regulation, such as DNA methylation, histone modifications and variants, plays a key role in controlling chromatin structure. A combination of multiple epigenetic marks exist at the whole genome level, and specific combinations of epigenetic marks are meaningful in biological function (Strahl and Allis, 2000). Epigenomic data sets are a rich resource to identify regulatory elements and functional annotations in coding and non-coding regions (ENCODE Project Consortium, 2012).

References:
(Strahl and Allis, 2000) The language of covalent histone modifications. Nature.
(ENCODE Project Consortium, 2012) An integrated encyclopedia of DNA elements in the human genome. Nature.

Source text:
(Liu et al., 2018) PCSD: a plant chromatin state database. Nucleic Acids Res.

Databases