DNA-Protein interactions databases
Chromatin is a genome-organizing platform, regulating gene expression, cell division and differentiation, etc. Epigenetic regulation, such as DNA methylation, histone modifications and variants, plays a key role in controlling chromatin structure. A combination of multiple epigenetic marks exist at the whole genome level, and specific combinations of epigenetic marks are meaningful in biological function. Epigenomic data sets are a rich resource to identify regulatory elements and functional annotations in coding and non-coding regions (ENCODE Project Consortium, 2012).