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DSRC | Compression of DNA sequence reads in FASTQ format

An application designed for compression of data files containing reads from DNA sequencing in FASTQ format. The amount of such files can be huge, e.g., a few (or tens) of gigabytes, so a need for a robust data compression tool is clear. Usually universal compression programs like gzip or bzip2 are used for this purpose, but it is obvious that a specialized tool can work better.

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DSRC classification

DSRC specifications

Unique identifier:
Software type:
Restrictions to use:
Programming languages:
C++, Python
Computer skills:
DNA Sequence Reads Compression
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
GNU General Public License version 2.0

DSRC distribution


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DSRC support


  • Sebastian Deorowicz <>


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Institute of Informatics, Silesian University of Technology, Gliwice; Computer Engineering Department, Technical University of Lodz, Lodz, Poland

Funding source(s)

This work was partially supported by the European Union from the European Social Fund within the INTERKADRA project UDAPOKL-04.01.01-00-014/10-00 and by the Polish National Science Centre under the project DEC-2012/05/B/ST6/03148.

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