Catalogs predicted non-B DNA-forming sequence motifs, including Z-DNA, G-quadruplex, A-phased repeats, inverted repeats, mirror repeats, direct repeats and their corresponding subsets. non-B DB assists users to construct hypotheses regarding the potential role of these structures in other cellular processes. It permits users to display: whole genome-level using Circos plots, chromosomal-level with custom histogram plots and nucleotide-level using the existing PolyBrowse interface.
Triplex Target DNA Site Mapping and Integration database provides a catalog of unique TTS locations in the human genome and tools for analyzing the co-localization of TTSs with genomic regulatory sequences and signals that were identified using next-generation sequencing techniques and/or predicted by computational models. TTSMI was designed as a user-friendly tool that facilitates (i) fast searching/filtering of TTSs using several search terms and criteria associated with sequence stability and specificity, (ii) interactive filtering of TTSs that co-localize with gene regulatory signals and non-B DNA structures, (iii) exploration of dynamic combinations of the biological signals of specific TTSs and (iv) visualization of a TTS simultaneously with diverse annotation tracks via the UCSC genome browser.
Contains 5,246 different genomes of bacterial and archaeal species, based on fully sequenced genomes and plasmids from the NCBI webserver (updated on 25 June 2014). In detail the database includes 3,173 different bacterial chromosomes and 2,073 plasmids. To our knowledge, this is the first database that allows selective searches for intrastrand triplexes.
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