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DNAPLOT specifications


Unique identifier OMICS_19798
Interface Web user interface
Restrictions to use None
Input data A single sequence or some multiple sequences.
Input format RAW, FASTA
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline VBASE2 Team <>

Additional information

http://www.vbase2.org/vbhelp.php DNAPLOT is a part of VBASE2 website.

Publications for DNAPLOT


VBASE2, an integrative V gene database.

2005 Nucleic Acids Res
PMCID: 540042
PMID: 15608286
DOI: 10.1093/nar/gki088
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller
werner muller

DNAPLOT citations


Characterization of Anti Citrinin Specific ScFvs Selected from Non Immunized Mouse Splenocytes by Eukaryotic Ribosome Display

PMCID: 4488840
PMID: 26131718
DOI: 10.1371/journal.pone.0131482

[…] right reading frame with no stop codon. the derived amino acid sequences and complementary determining regions (cdrs) are shown in the framework regions (frs) and cdrs were determined by the v-base dnaplot software. the length of cdrs was variable. the length of cdr1 vh ranged from 9 to 11 amino acid residues, with an average length of 10 residues, cdr2 vh with an average length of 7 residues, […]


Decreased Mutation Frequencies among Immunoglobulin G Variable Region Genes during Viremic HIV 1 Infection

PMCID: 3883639
PMID: 24409278
DOI: 10.1371/journal.pone.0081913

[…] somatic hypermutations were identified by comparing the sequences to the vbase (http://vbase.mrc-cpe.cam.ac.uk/) database of variable region germline sequences using the dnaplot software. multiple identical sequences were excluded from analysis and the percent of sequences excluded did not differ between group (median percent of redundant sequences relative […]


Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential

PMCID: 3929437
PMID: 24256717
DOI: 10.4161/mabs.27236

[…] of both heavy and light chain genes (fragment size ~1kb). sequences from at least five intact, randomly chosen scfvs per sublibrary were determined and analyzed by sequence alignment software dnaplot (http://www2.mrc-lmb.cam.ac.uk/vbase/dnaplot2.php) to identify the closest germline v, (d), and j segment genes as deposited in vbase. complementarity-determining regions (cdrs) […]


A tailored health surveillance program unveils a case of MALT lymphoma in an HCV positive health care worker

PMCID: 3573080
PMID: 23420489
DOI: 10.3892/ol.2012.1028

[…] were purified by gel electrophoresis, then sequenced. the most similar vh and dh germline gene segments were identified by sequence comparison to the international immunogenetics database with dnaplot software (http://imgt.cines.fr)., dna was isolated from tumour samples by standard phenol-chloroform extraction. t(14;18)-(igh;bcl-2) translocation, at the major break point region (mbr) […]


Critical Epitopes in the Nucleocapsid Protein of SFTS Virus Recognized by a Panel of SFTS Patients Derived Human Monoclonal Antibodies

PMCID: 3373585
PMID: 22719874
DOI: 10.1371/journal.pone.0038291

[…] of phage panning, individual clones from enriched phage pools were analyzed by elisa against sfts virions or purified n protein. the positive human fab clones were sequenced and aligned with the dnaplot program for alignment to the vbase database. the human fab antibodies selected based on binding activity and sequence variance were converted to human igg by cloning the fab genes […]


Selection of Anti Sulfadimidine Specific ScFvs from a Hybridoma Cell by Eukaryotic Ribosome Display

PMCID: 2712767
PMID: 19641611
DOI: 10.1371/journal.pone.0006427

[…] three scfvs and complementary determining regions (cdr) were shown in . by using the dna sequences, the vh and vl gene families of the scfvs were designated based on werner müller's database (dnaplot software). the heavy chains of scfvs sas68 and sas71 belong to the vh1 gene family and that of sas14 belongs to the vh2 gene family. the light chains of clones sas68 and sas71 belong […]

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DNAPLOT institution(s)
Department of Experimental Immunology, Helmholtz Centre for Infection Reseach, Braunschweig, Germany

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