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Dose-response relationship tools

Understanding the dose–response relationship of therapeutic compounds is a major focus of clinical oncology.

Source text:
(Tong et al., 2015) drexplorer: A tool to explore dose-response relationships and drug-drug interactions. Bioinformatics.

TCPl
Desktop

TCPl ToxCast Data Analysis Pipeline

A generalized platform for storing, normalizing, and dose-response modeling of…

A generalized platform for storing, normalizing, and dose-response modeling of large high-throughput and high-content chemical screening data. The tcpl package provides functionality for two…

BMDExpress…
Desktop
Web

BMDExpress Data Viewer

A web-based application for visualizing and graphing BMDExpress output files.…

A web-based application for visualizing and graphing BMDExpress output files. BMDExpress applies BMD modeling to transcriptomic datasets to identify transcriptional BMDs. Through our case studies, we…

QDREC
Web

QDREC Quantal Dose Response Calculator

A web server for automatically determining quantal dose-response…

A web server for automatically determining quantal dose-response characteristics of macroparasites in phenotypic drug screening. Such parasites include the etiological agents of tropical diseases…

drexplorer
Desktop

drexplorer

Nonlinear dose-response models are primary tools for estimating the potency…

Nonlinear dose-response models are primary tools for estimating the potency (e.g., half-maximum inhibitory concentration known as IC50) of anticancer drugs. drexplorer enables biologists to evaluate…

DoseFinding
Desktop

DoseFinding

Provides functions for the design and analysis of dose-finding experiments…

Provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting…

Dr Fit
Desktop

Dr Fit Dose-Response FITting

Enables fitting dose-response curves with complex multiphasic features. Dr Fit…

Enables fitting dose-response curves with complex multiphasic features. Dr Fit is a software that reads the dose-response data and builds the model. The algorithm implemented in Dr-Fit first attempts…

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