Understanding the dose–response relationship of therapeutic compounds is a major focus of clinical oncology. Source text: Tong et al., 2015.
Desktop app
ToxCast Data Analysis… ToxCast Data Analysis Pipeline

TCPl ToxCast Data Analysis Pipeline

A generalized platform for storing, normalizing, and dose-response modeling of…

A generalized platform for storing, normalizing, and dose-response modeling of large high-throughput and high-content chemical screening data. The tcpl package provides functionality for two…

Desktop app
Web app
BMDExpress Data Viewer BMDExpress Data Viewer

BMDExpress Data Viewer

A web-based application for visualizing and graphing BMDExpress output files.…

A web-based application for visualizing and graphing BMDExpress output files. BMDExpress applies BMD modeling to transcriptomic datasets to identify transcriptional BMDs. Through our case studies, we…

Desktop app
Dose-Response FITting Dose-Response FITting

Dr Fit Dose-Response FITting

Enables fitting dose-response curves with complex multiphasic features. Dr Fit…

Enables fitting dose-response curves with complex multiphasic features. Dr Fit is a software that reads the dose-response data and builds the model. The algorithm implemented in Dr-Fit first attempts…

Web app
Quantal Dose Response… Quantal Dose Response Calculator

QDREC Quantal Dose Response Calculator

A web server for automatically determining quantal dose-response…

A web server for automatically determining quantal dose-response characteristics of macroparasites in phenotypic drug screening. Such parasites include the etiological agents of tropical diseases…

Desktop app
DoseFinding DoseFinding

DoseFinding

Provides functions for the design and analysis of dose-finding experiments…

Provides functions for the design and analysis of dose-finding experiments (with focus on pharmaceutical Phase II clinical trials). It provides functions for: multiple contrast tests, fitting…

Desktop app
drexplorer drexplorer

drexplorer

Nonlinear dose-response models are primary tools for estimating the potency…

Nonlinear dose-response models are primary tools for estimating the potency (e.g., half-maximum inhibitory concentration known as IC50) of anticancer drugs. drexplorer enables biologists to evaluate…

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