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DP-Bind specifications


Unique identifier OMICS_03581
Name DP-Bind
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Igor B. Kuznetsov <>

Publication for DP-Bind

DP-Bind citations


Characterization of the DNA binding activity of structural protein VP1 from chicken anaemia virus

PMCID: 5936033
PMID: 29728113
DOI: 10.1186/s12917-018-1465-5

[…] region within the n-terminus of vp1 contains high arginine content and might confer an ability to vp1 to bind and protect dna []. using online software, including psort ii (http://psort.hgc.jp) and dp-bind (lcg.rit.albany.edu/dp-bind/), the vp1 protein was analysed in this study. a total of four putative dna-binding motifs and two putative nlss were found and predicted within the cav vp1, […]


The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation

PMCID: 5557760
PMID: 28811474
DOI: 10.1038/s41467-017-00279-z

[…] out-competed the labeled fragment for binding to ptpa.fig. 5 , to further determine the dna-binding region within ptpa, we predicted residue positions of ptpa involved in interactions with dna by dp-bind (fig. ), a web server for sequence-based prediction of dna-binding residues in dna-binding proteins, and constructed three deletion mutants of ptpa (ptpa δ1-20, ptpa δ41-49, and ptpa δ65-75) […]


mRNA Quantification of NIPBL Isoforms A and B in Adult and Fetal Human Tissues, and a Potentially Pathological Variant Affecting Only Isoform A in Two Patients with Cornelia de Lange Syndrome

PMCID: 5372497
PMID: 28241484
DOI: 10.3390/ijms18030481

[…] (c). peak levels were found in the fetal kidney, spleen, and thymus, and the adult pancreas and liver (53–47-fold), and minimum levels were found in adult skeletal muscle and the brain (c)., dp-bind server (http://lcg.rit.albany.edu/dp-bind), a system for the sequence-based prediction of dna-binding residues in proteins, suggested that the c-terminal segment of nipbl isoform a (residues […]


TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation

PMCID: 5080701
PMID: 27782840
DOI: 10.1186/s12915-016-0318-6

[…] this minimal essential region for tis7-mediated activation of icln transcription. using bioinformatics prediction software (disis (www.predictprotein.org), bindn+ (http://bioinfo.ggc.org/bindn+/), dp-bind (http://lcg.rit.albany.edu/dp-bind/), and dnabindr (http://turing.cs.iastate.edu/preddna/); additional file : figure s2) we identified, with 70–80 % probability, three distinct dna-binding […]


Structural basis for LIN54 recognition of CHR elements in cell cycle regulated promoters

PMCID: 4974476
PMID: 27465258
DOI: 10.1038/ncomms12301

[…] create a structural model for dream bound to dna (). consistent with reported footprinting data, lin54 contacts the minor groove and e2f-dp binds the major groove. the model shows that lin54 and e2f-dp bind the dna helix on opposite faces. we found that three or four base pairs is the closest the two dna sequence elements can be without steric clashes between the two bound dbds., […]


Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility

PMCID: 4741053
PMID: 26847345
DOI: 10.1186/s12885-016-2105-8

[…] transgelin localized partially in the nucleus of the crc cells; it shares 85 % similarity to tagln3, which is believed to be a transcriptional regulator []; bioinformatic analysis using the dp-bind web server (http://lcg.rit.albany.edu/dp-bind) identified several segments of transgelin as having high dna-binding potential (data not shown); studies also suggests that nuclear […]

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DP-Bind institution(s)
Gen*NY*Sis Center for Excellence in Cancer Genomics, Department of Epidemiology and Biostatistics, One Discovery Drive, University at Albany, Rensselaer, NY, USA

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