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Driver gene fusion prediction software tools | RNA sequencing data analysis

Given the unprecedented sensitivity of gene fusion detection, and the repeated identification of fusion transcripts in normal cells, it is increasingly important to separate driver fusions from passenger mutations. Although many fusion detection…
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Oncofuse
Desktop

Oncofuse

A robust Bayesian classifier for the classification of fusion sequences.…

A robust Bayesian classifier for the classification of fusion sequences. Oncofuse predicts the oncogenic potential of novel fusion genes, calculating the probability that a fusion sequence behaves as…

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Chimera
Desktop

Chimera

Allows users to manipulate, analyze and filter fusion events detected by a…

Allows users to manipulate, analyze and filter fusion events detected by a variety of fusion detection tools. Chimera performs a first step of validation, which can be useful given the high number of…

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Fusion…
Desktop

Fusion centrality

A systematic and effective method for prioritizing fusion drivers from hundreds…

A systematic and effective method for prioritizing fusion drivers from hundreds or thousands of fusion candidates identified in diverse cancer types. We first propose a domain-based fusion model…

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Pegasus
Desktop

Pegasus

A pipeline for the annotation and prediction of biologically functional gene…

A pipeline for the annotation and prediction of biologically functional gene fusion candidates. Pegasus provides a common interface for various gene fusion detection tools, reconstruction of novel…

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