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Cancer driver databases | Genome variation analysis

Massively parallel sequencing technologies have enabled characterization of genomic alterations across multiple tumor types. Efforts have focused on identifying driver mutations because they represent potential targets for therapy. However, because…
DriverDB
Dataset

DriverDB

Incorporates approximately 6000 cases of exome-seq data, in addition to…

Incorporates approximately 6000 cases of exome-seq data, in addition to annotation databases and published bioinformatics algorithms dedicated to driver gene/mutation identification. The database…

IntOGen
Dataset

IntOGen

A resource for the cancer research community that facilitates interrogation of…

A resource for the cancer research community that facilitates interrogation of a substantial amount of data from genome-wide analyses. The current version contains data from almost 800 independent…

MutationView
Dataset

MutationView

Consists in a human gene mutation database.

Consists in a human gene mutation database.

CanDL
Dataset

CanDL Cancer Driver Log

Hosts driver mutations in cancers that are potentially actionable to support…

Hosts driver mutations in cancers that are potentially actionable to support annotation in clinical genomic testing laboratories by molecular pathologists, laboratory directors, and…

SBCDDB
Dataset

SBCDDB Sleeping Beauty Cancer Driver DataBase

Couples statistical tests with spatial information to provide context behind…

Couples statistical tests with spatial information to provide context behind decisions identifying cancer driver genes. SBCDDB is a database that contains 19 primary mouse models of human tumor types…

Kin-Driver
Dataset

Kin-Driver

Compiles driver mutations in protein kinases (PKs) with experimental evidence…

Compiles driver mutations in protein kinases (PKs) with experimental evidence demonstrating their functional role. Kin-driver is a manual expert-curated database that pays special attention to…

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