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DriverDB specifications


Unique identifier OMICS_00268
Name DriverDB
Restrictions to use None
Database management system MySQL
Data access Browse
Version 2.0
Maintained Yes


  • Primates
    • Homo sapiens

Publications for DriverDB

DriverDB citations


APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism

Nat Commun
PMCID: 5587710
PMID: 28878238
DOI: 10.1038/s41467-017-00493-9

[…] statically significant amplified or deleted regions. Genes located within the putative amplified/deleted regions were further checked whether they are reported to be a driver mutation gene in HNSC in driverDB. CNVs for 50 OSCC patients from India were obtained from a supplementary table of the relevant study. […]


An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer

PLoS Comput Biol
PMCID: 4575033
PMID: 26379039
DOI: 10.1371/journal.pcbi.1004350

[…] endrix, DriverNet, MuSiC, and MEMo [, , , –] were also developed to identify driver pathways using network-based approaches. An integrated meta-analysis using multiple methods can be accessed through DriverDB [].Here we describe a computational approach designed to identify alterations that act as drivers during tumorigenesis. We first designed a mathematical model of the evolutionary processes of […]


Computational methods and resources for the interpretation of genomic variants in cancer

BMC Genomics
PMCID: 4480958
PMID: 26111056
DOI: 10.1186/1471-2164-16-S8-S7

[…] Browser allows better visualization of clinical data.Other three interesting resources for the analysis of cancer genome data are the Cancer Gene annotation system for Cancer Genomics (CaGe) [], the DriverDB [] and the Integrative Oncogenomics Cancer Browser (IntOGen) []. CaGe is a cancer genome annotation system for the classification of candidate genes from cancer genome studies, using either p […]


Human cancer databases (Review)

PMCID: 4254674
PMID: 25369839
DOI: 10.3892/or.2014.3579

[…] various tumors, oncogenicity, chromosomal location, tumor gene type (either proto-oncogene or tumor suppressor gene) and the signal transduction pathways in which the gene of interest is involved.The DriverDB database () compiles a large amount (>6,000 cases) of exome-sequencing (exome-seq) data, annotation databases such as dbSNP (), 1000 Genome () and COSMIC, as well as various bioinformatics al […]


The 2014 Nucleic Acids Research Database Issue and an updated NAR online Molecular Biology Database Collection

Nucleic Acids Res
PMCID: 3965027
PMID: 24316579
DOI: 10.1093/nar/gkt1282

[…] otide variants, indels and copy-number variants; and the Database of Genomic Variants (DGV) at the Toronto’s Centre for Applied Genomics (). There are also several more specialized databases (canSAR, DriverDB, FINDBase, HbVar, Lynx, NECTAR, Progenetix) that cover genetic defects leading to various human diseases, including cancer. In addition, three separate databases, Selectome, dbPSHP and 1000 G […]


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DriverDB institution(s)
Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan; Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei, Taiwan; Research Center for Tumour Medical Science, China Medical University, Taichung, Taiwan; Department of Genome Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Cancer Biology, China Medical University, Taichung, Taiwan; VGH-YM Genomic Research Center, National Yang-Ming University, Taipei, Taiwan; Institute of Clinical Medicine, Medical College, National Yang-Ming University, Taipei, Taiwan; Institute of Microbiology and Immunology, National Yang-Ming University, Taipei, Taiwan; Department of Education and Research, Taipei City Hospital, Taipei, Taiwan
DriverDB funding source(s)
Ministry of Science and Technology (MOST) [104-2221-E-010-012, 104-2320-B-039-053]; China Medical University, Taiwan [CMU104-N-14]; National Yang-Ming University, Taiwan (a grant from the Ministry of Education, Aim for the Top University Plan)

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