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DroSpeGe specifications


Unique identifier OMICS_03125
Name DroSpeGe
Alternative name Drosophila Species Genomes
Restrictions to use None
Maintained Yes


  • Invertebrates
    • Drosophila melanogaster

Publication for Drosophila Species Genomes

DroSpeGe citations


Rapidly Evolving Toll 3/4 Genes Encode Male Specific Toll Like Receptors in Drosophila

Mol Biol Evol
PMCID: 5850136
PMID: 28541576
DOI: 10.1093/molbev/msx168

[…] To compile a detailed compendium of all Toll paralogs, we first identified all Tolls from a well-assembled, well-annotated set of 12 Drosophila species genomes (), using blastn and tblastn searches with D. melanogaster Toll-1 to -9 as queries. We extracted the amino acid sequences from the TIR domain of all Toll proteins, generated […]


Analyses of Nuclearly Encoded Mitochondrial Genes Suggest Gene Duplication as a Mechanism for Resolving Intralocus Sexually Antagonistic Conflict in Drosophila

Genome Biol Evol
PMCID: 2995371
PMID: 21037198
DOI: 10.1093/gbe/evq069

[…] for the 498 nuclearly encoded mitochondrial genes were downloaded from FlyBase (http://flybase.org/) to perform BlastP searches () against the annotated protein sequence databases of the 12 sequenced Drosophila species genomes (D. melanogaster, D. simulans, D. sechellia, D. yakuba, D. erecta, D. ananassae, D. pseudoobscura, D. persimilis, D. willistoni, D. mojavensis, D. virilis, and D. grimshawi) […]


Contrasting Patterns of Transposable Element Insertions in Drosophila Heat Shock Promoters

PLoS One
PMCID: 2793543
PMID: 20041194
DOI: 10.1371/journal.pone.0008486

[…] To obtain orthologues of D. melanogaster genes from Drosophila species genomes, BLASTn and tBLASTn were performed at the Flybase website with D. melanogaster coding sequences, gene region sequences, or protein sequences. BLAST was performed to D. mela […]


Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno 3

BMC Genet
PMCID: 2767349
PMID: 19840385
DOI: 10.1186/1471-2156-10-67

[…] umber of exons and positions of exon junctions in D. pseudoobscura mRNA, a few longest sequences of Bru-3 were BLASTed [BLASTN, []] against the genomic sequence of D. pseudoobscura [r2.0.1, []] using Drosophila Species Genomes BLAST [DroSpeGe, []92]. We verified that the 5' (donor) and 3' (acceptor) SSs flanking introns [i.e., GT and AG, []] were directly adjacent to each inferred exon junction in […]


Gene Expression Disruptions of Organism versus Organ in Drosophila Species Hybrids

PLoS One
PMCID: 2500191
PMID: 18714377
DOI: 10.1371/journal.pone.0003009

[…] (dj), and Mst84D) and an endogenous control gene (Actin5C), were collected from NCBI (http://www.ncbi.nlm.nih.gov/). The D. melanogaster DNA sequence was BLASTed against the D. simulans genome using Drosophila Species Genomes BLAST (http://insects.eugenes.org/species/blast/). The D. simulans genes were aligned with the orthologous D. melanogaster sequences. Primers were designed to sequence regio […]


The non dosage compensated Lsp1α gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes

BMC Mol Biol
PMCID: 1890558
PMID: 17511883
DOI: 10.1186/1471-2199-8-35
call_split See protocol

[…] P1α (GenBank accession no. NP_511138), LSP1β (GenBank accession no. NP_476624) and LSP1γ (GenBank accession no. NP_523868) protein sequences were used to search the nucleotide sequences available in "DroSpeGe: Drosophila Species Genomes" [] using tBlastn . The scaffolds on which the LSP1 homologues were identified are described in additional files and . LSP1β and LSP1γ had independently been iden […]


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DroSpeGe institution(s)
Department of Biology, Indiana University, Bloomington, IN, USA

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