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Drug-target interaction databases

There are at least two good reasons for the on-going interest in drug-target interactions: first, drug-effects can only be fully understood by considering a complex network of interactions to multiple targets (so-called off-target effects) including metabolic and signaling pathways; second, it is crucial to consider drug-target-pathway relations for the identification of novel targets for drug development.

Source text:
(Hecker et al., 2012) SuperTarget goes quantitative: update on drug-target interactions. Nucleic Acids Res.

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