Performs drug set enrichment analysis for a drug list in drug sets based on hypergeometric test. DrugPattern is a web application able to collect and curate more of 7000 drug sets, which cover a number of big categories, such as drug targets, pathways, chemical classification, diseases, and adverse reaction. For a given list of drugs, DrugPattern then calculated the enrichment of these drugs in each of the drug sets.
Department of Biomedical Informatics, Department of Physiology and Pathophysiology, MOE Key Lab of Cardiovascular Sciences, School of Basic Medical Sciences, Peking University, Beijing, China; School of Mathematics Sciences, Huaqiao University, Quanzhou, China; Hypertension Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Beijing, China; Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Gender in Medicine and Center for Cardiovascular Research, and DZHK (German Centre for Cardiovascular Research), partner site Berlin, Germany; Center of Bioinformatics, Key Laboratory for Neuro-Information of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu, China
DrugPattern funding source(s)
Supported by National Natural Science Foundation of China (81422006 and 81670462; 81670748 and 81471035) and Beijing Natural Science Foundation (7171006).