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DTK specifications


Unique identifier OMICS_30382
Name DTK
Alternative name Diffusion Toolkit
Software type Toolkit/Suite
Interface Command line interface, Graphical user interface
Restrictions to use None
Input format DICOM
Operating system Unix/Linux, Mac OS, Windows
Programming languages C++
Computer skills Advanced
Stability Stable
Registration required Yes
Maintained Yes


No version available


  • person_outline DTK Team

Additional information


DTK citations


The effect of the total small vessel disease burden on the structural brain network

Sci Rep
PMCID: 5945601
PMID: 29748646
DOI: 10.1038/s41598-018-25917-4
call_split See protocol

[…] Corrections for eddy current and head motions were performed by coregistering all DWIs to b0 using FMRIB’s Diffusion Toolbox. Diffusion Toolkit was also used to estimate the diffusion tensor using the linear least-squares fitting method. To construct the structural connections between the 90 brain regions, deterministic whol […]


Impaired Prefrontal Amygdala Pathway, Self Reported Emotion, and Erection in Psychogenic Erectile Dysfunction Patients With Normal Nocturnal Erection

Front Hum Neurosci
PMCID: 5928255
PMID: 29740301
DOI: 10.3389/fnhum.2018.00157
call_split See protocol

[…] g, eddy current distortions and motion artifact were corrected. The main pipeline processing steps included diffusion tensor estimation, FA calculation and fiber tract reconstruction (Chen et al., ). Diffusion toolkit toolbox (http://www.trackvis.org) was implemented to reconstruct the fiber tracts. The whole-brain fiber tracking was performed based on the Fiber Assignment by Continuous Tracking ( […]


In Vivo Multimodal Magnetic Resonance Imaging Changes After N Methyl d Aspartate Triggered Spasms in Infant Rats

PMCID: 5911983
PMID: 29713308
DOI: 10.3389/fneur.2018.00248
call_split See protocol

[…] application of diffusion gradient pulses, a 4-ms diffusion gradient duration (δ), a gradient amplitude (G) of 46.52 mT/m, and the Jones 30 gradient scheme.Postprocessing analysis was performed using Diffusion Toolkit software (http://trackvis.org/). The cingulate cortex of each rat was selected and the fractional anisotropy (FA) and mean diffusivity (MD) were calculated from the diffusion tensor […]


Disrupted Module Efficiency of Structural and Functional Brain Connectomes in Clinically Isolated Syndrome and Multiple Sclerosis

Front Hum Neurosci
PMCID: 5902485
PMID: 29692717
DOI: 10.3389/fnhum.2018.00138

[…] Diffusion MRI tractography was performed to reconstruct the whole-brain fiber streamlines with Diffusion Toolkit. All the tracts in the dataset were computed by seeding each voxel with an FA greater than 0.2. The tractography was terminated if it turned an angle greater than 45 degrees or reach […]


Influence of region of interest designs on quantitative measurement of multimodal imaging of MR non enhancing gliomas

PMCID: 5920197
PMID: 29725480
DOI: 10.3892/ol.2018.8319
call_split See protocol

[…] with a 128×128 spatial resolution for a 260×260 mm field of view. A total of 50 sections were obtained, with a section thickness of 3 mm and no intersection gap. ADC and FA maps were processed using Diffusion Toolkit (Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA; http://www.trackvis.org/dtk/). […]


Do blast induced skull flexures result in axonal deformation?

PLoS One
PMCID: 5856259
PMID: 29547663
DOI: 10.1371/journal.pone.0190881

[…] s–using the multi-block meshing capability in ANSYS ICEM CFD. shows the high-quality hexahedral meshes belonging to the male and female T1-MRI data, respectively.Axonal tractography, developed using Diffusion Toolkit (www.trackvis.org/dtk) and TrackVis (www.trackvis.org), was converted into a finite element truss mesh. The resultant tractography, of male and female, has 9452 and 9771 axonal tract […]


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DTK institution(s)
Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA
DTK funding source(s)
Supported by MGH GCRC and NIMH Grant 5R01MH064044.

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