DTome statistics

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Citations per year

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Popular tool citations

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Tool usage distribution map

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Associated diseases

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DTome specifications

Information


Unique identifier OMICS_05508
Name DTome
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained No

Maintainer


This tool is not available anymore.

Publication for DTome

DTome in publications

 (3)
PMCID: 5122419
PMID: 27232943
DOI: 10.18632/oncotarget.9578

[…] activities of resveratrol might be gleaned by systematically dissecting the publicly available published data on chemicals and drugs. in this study, we tested our hypothesis by querying dtome (drug-target interactome), a web-based tool containing data compiled from open-source databases including drugbank, pharmgsk, and protein interaction network analysis (pina). four direct […]

PMCID: 4823946
PMID: 26986512
DOI: 10.1038/cddis.2016.45

[…] interaction network is generated by combining the hprd, ophid, bind, and mint databases, and has a similar degree of interactions for both disease and non-disease proteins., we used the dtome web-based tool for drug–target interactome construction (http://bioinfo.mc.vanderbilt.edu/dtome). the dtome tool utilizes web-based queries to search candidate drugs and then construct a dtome […]

PMCID: 3216539
PMID: 22355571
DOI: 10.1038/srep00052

[…] to date. we report a computational approach that combines different sources of drug and protein interaction information to assemble the myocardial infarction drug-target interactome network (my-dtome). my-dtome comprises approved and other drugs interlinked in a single, highly-connected network with modular organization. we show that approved and other drugs may both be highly connected […]


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DTome institution(s)
Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA; Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, USA; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN, USA
DTome funding source(s)
Partially supported by a 2010 NARSAD Young Investigator Award and the NIH grant NCI R01CA141307.

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