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Duplicate read removal software tools | High-throughput sequencing data analysis

The presence of duplicates introduced by PCR amplification is a major issue in paired short reads from next-generation sequencing platforms. These duplicates might have a serious impact on research applications, such as scaffolding in whole-genome sequencing and discovering large-scale genome variations, and are usually removed.

Source text:
(Xu et al., 2012) FastUniq: a fast de novo duplicates removal tool for paired short reads. PLoS One.

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