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dyebias | Adaptable gene-specific dye bias correction for two-channel DNA microarrays

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A correction method whereby sequence-specific corrections are modulated by the overall bias of individual hybridizations. GASSCO outperforms earlier methods and works well on a variety of publically available datasets covering a range of platforms, organisms and applications, including ChIP on chip. Given a reasonable number of dye-swapped pairs of hybridizations, or of same vs. same hybridizations, both the gene- and slide-biases can be estimated and corrected using the GASSCO method.

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dyebias classification

dyebias specifications

Unique identifier:
OMICS_02025
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Maintained:
Yes

dyebias distribution

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dyebias support

Documentation

Credits

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Publications

Institution(s)

Department of Physiological Chemistry, University Medical Center Utrecht, Universiteitsweg, Utrecht, Netherlands

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