DynGO statistics

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DynGO specifications


Unique identifier OMICS_14126
Name DynGO
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java
License GNU General Public License version 3.0
Computer skills Medium
Stability No
Perl, BerkeleynD8, Perl model BerkeleyD8
Maintained No


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Publication for DynGO

DynGO in publications

PMCID: 5904110
PMID: 29666374
DOI: 10.1038/s41467-018-03936-z

[…] a-11001,1:2500) in ps for 1 h, and the nuclei were stained by hoechst 33258 (sigma) (1:10,000). inhibitors against endocytosis mechanisms was used as follows: the cells were pre-incubated with dyngo-4a (abcam) (50 µm), which blocks dynamin and/or eipa (80 µm), an amiloride that blocks na+/h+ exchangers, for 30 min prior to infection. hatric-coupled or non-coupled virus was submitted […]

PMCID: 5828446
PMID: 29486010
DOI: 10.1371/journal.pone.0193302

[…] in the cytoplasm of bv2 and c8-d1a cells, unlike untreated or dyngo4a treated cells. the nuclear to cytoplasmic ratio of ang increased and plateaued over the four hour time course in untreated and dyngo4 treated bv2 and c8-d1a cells (). in contrast, dynasore treatment of these cells resulted in a nearly even distribution of ang between the nucleus and cytoplasm at four hours i.e. less nuclear […]

PMCID: 5792449
PMID: 29420171
DOI: 10.1016/j.celrep.2017.12.089

[…] or be enhanced, by receptor internalization that would contribute to sustained (i.e., non-canonical) signaling. to test this hypothesis, we treated hek293-casr cells with the dynamin-blocking agent dyngo, which would abolish endocytosis and prevent endosomal signaling, and assessed their mapk signaling responses by measurement of perk1/2 to a 5 min pulse of 5 mm ca2+e. perk1/2 accumulated […]

PMCID: 5897098
PMID: 29553370
DOI: 10.7554/eLife.34798.042

[…] and (3) donkey anti-goat tertiary antibodies, for 30 min each at 4°c, in pbs containing ca2+, mg2+ and 0.1% glucose. labeled cells were then incubated 30 min at 37°c in the presence of 30 μm dyngo 4a, to patch crosslinked cr3 without its internalization. following this treatment, cells were treated 10 min with or without 1 μm latrunculin a, in the presence of 1 μm n-ethylmaleimide […]

PMCID: 5811214
PMID: 29381137
DOI: 10.7554/eLife.33012.023

[…] ligand-dependent internalization of the transferrin receptor, and assessed whether internalization of transferrin is perturbed in distal axons (). compared to the dmso vehicle control, treatment of dyngo, a dynamin inhibitor, completely abolished internalization of transferrin, but not bsa, which is internalized by fluid-phase endocytosis (). these findings indicate the presence […]

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DynGO institution(s)
Department of Information Systems, University of Maryland, Baltimore County, MD, USA; Department of Biochemistry and Molecular Biology, Georgetown University Medical Center, WA, USA
DynGO funding source(s)
The project is supported by grant IIS-0430743 from the National Science Foundation.

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