Dataset features

Specifications


Application: Peptide array analysis
Number of samples: 156
Release date: Jul 6 2012
Last update date: Jul 6 2012
Access: Public
Diseases: Tuberculosis
Dataset link Profiling proteome-scale antibody responses to M. tuberculosis proteins in sera of macaques infected with M. tuberculosis

Experimental Protocol


To investigate antibody responses during the course of infection, we probed M. tuberculosis proteome microarrays with serial sera collected from experimentally infected cynomolgus macaques. Based on infection outcome, the macaques were grouped into three classes; A) active disease (n = 4), B) latent infection (n=5) and C) reactivation disease (n = 5). Note that the macaques in the reactivation class developed signs of disease spontaneously without any experimental intervention. For each animal, we tested one pre-infection time point and approximately ten post-infection time points at one-month intervals.

Repositories


GEO

GSE30721

ArrayExpress

E-GEOD-30721

BioProject

PRJNA154689

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Contact


Shajo Kunnath-Velayudhan