Dataset features

Specifications


Dataset type: Expression profiling by array, transcription profiling by array, Transcriptome or Gene expression
Number of samples: 16
Release date: Jan 15 2016
Last update date: Jan 12 2017
Access: Public
Diseases: Cardiomegaly, Myocardial Infarction, Hypertrophy, Fibrosis, Heart Murmurs
Chemicals: Nitric Oxide
Dataset link Cardiomyocyte-specific Nitric Oxide Synthase 3 Overexpression in Pressure-Overloaded Left Ventricle.

Experimental Protocol


Left ventricular mRNA expression profiles were compared between alpha-myosin heavy chain driven nitric oxide synthase 3 (alpha-MHC-NOS3) transgenic and wild type (WT) littermate mice at baseline and 10 weeks after transversal aortic constrcition-induced pressure-overload. Biological repeats: n=4, two males and two females, for each group and condition. Transgenic mice were backcrossed for seven generations (F7) to a C57Bl/6 N background and age and weight matched animals were used for microarray experiments.

Repositories


GEO

GSE37597

ArrayExpress

E-GEOD-37597

BioProject

PRJNA162561

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Contact


Wouter Van Delm