Computational protocol: Genetic parameters and allele frequencies of five new European Standard Set STR loci (D10S1248, D22S1045, D2S441, D1S1656, D12S391) in the population of Romania

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Protocol publication

[…] For all autosomal 15 loci of Investigator ESSplex Plus Kit, observed heterozygosity, expected heterozygosity, and P-values of the Hardy-Weinberg equilibrium tests were assessed using GDA version 1.1 () and also matching probability, power of discrimination, polymorphism information content, probability of exclusion, and typical paternity index were calculated with a modified version of Powerstats Version 1.2 (). Population differentiation tests were carried out using allele frequencies from previously published population data for the new five ESS loci (Austria, Belgium, Croatia, Czech, Germany, Hungary, Italy, Macedonia, Poland, Portugal, Spain, Sweden, and United Kingdom) using Arlequin Software version 3.1.1 (). […]

Pipeline specifications

Software tools GDA, Arlequin
Applications Population genetic analysis, GWAS
Organisms Homo sapiens